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bio-clinical-databases-gnomad-frequencies

Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOE…

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Open / InstallLast updated July 27, 2026

Description

Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples). A reusable SKILL.md agent skill by GPTomics.

Author

GPTomics

Platform

cli

Pricing model

free

Categories

Skills

Tags

skill
claude-skill
github
en

Capabilities

  • 1,053 stars
  • SKILL.md package