bio-clinical-databases-polygenic-risk
Constructs and validates polygenic risk scores using LDpred2-auto, SBayesRC, MegaPRS, PRS-CS, PROSPER, MUSSEL, BridgePR…
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Open / InstallLast updated July 27, 2026
Description
Constructs and validates polygenic risk scores using LDpred2-auto, SBayesRC, MegaPRS, PRS-CS, PROSPER, MUSSEL, BridgePRS, JointPRS, PRSmix, or PGS Catalog Calculator with ancestry-aware reference panels (HapMap3, UKB-LD), ancestry-conditional calibration, and PRS-RS reporting standards. Use when computing PRS for cohorts, applying absolute-risk transformation, assessing cross-ancestry portability (Martin 2017 / Ding 2023 continuous ancestry), or auditing PRS manuscripts against the 22-item PRS-RS reviewer checklist. A reusable SKILL.md agent skill by GPTomics.
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Author
GPTomics
Platform
cli
Pricing model
free
Categories
- Skills
Tags
- skill
- claude-skill
- github
- en
Capabilities
- 1,053 stars
- SKILL.md package
Information
TypeSkill
SourceSkillsmp
AddedJuly 27, 2026