Write a systematic review protocol into `output/PROTOCOL.md` (databases, queries, inclusion/exclusion, time window, ext…
Write a systematic review protocol into `output/PROTOCOL.md` (databases, queries, inclusion/exclusion, time window, extraction fields). **Trigger**: protocol, PRISMA, systematic review, inclusion/exclusion, 检索式, 纳入排除. **Use when**: systematic review pipeline 的起点（C1），需要先锁定 protocol 再开始 screening/extraction。 **Skip if**: 不是做 systematic review（或 protocol 已经锁定且不允许修改）。 **Network**: none. **Guardrail**: protocol 必须包含可执行的检索与筛选规则；需要 HUMAN 签字后才能进入 screening。
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